S4E10: Nathan Spreng-认知网络及其如何随年龄和疾病变化

2024-02-19 08:09:25109:28 54
所属专辑:OHBM Podcast
声音简介

如果你对与Nathan合作感兴趣,他目前正在招聘博士后!请发送你的简历至 lbc.spreng@gmail.com

今天我们的嘉宾是Nathan SprengSpreng博士是麦吉尔大学蒙特利尔神经学院与医院的James McGill神经学和神经外科教授,以及脑与认知实验室的主任。

作为本科生,Spreng博士最初对诗歌专业感兴趣,直到他上了一堂心理学课程,激发了他对大脑的兴趣。他在2008年从多伦多大学BrianLevine的实验室获得了博士学位,并在多伦多大学的CherylGrady和哈佛大学的Dan Schacter那里做博士后研究。在康奈尔大学担任助理教授约5年后,他转到了麦吉尔大学。

在他的职业生涯中,Spreng博士一直使用功能性磁共振成像(fMRI)来揭示与注意力、记忆、认知控制和社会认知相关的微妙而可重复的大尺度脑网络。他还帮助阐明了默认网络在自我生成思维中的中心作用,以及它如何与大脑中的多个系统动态交互。

在这一集中,PeterNathan进行了一次广泛的对话,讨论了他的工作及其含义,涵盖了他对静息态海马联结网络集合体年龄依赖性的研究、如何从绘制网络过渡到建模和理解机制、他的工作可能的多种临床含义、当前对阿尔茨海默病的理解、我们对多回波EPI的共同欣赏、他的有关一个大型多回波EPI和结构MRI数据集的数据公开论文,以及更多内容。

祝您收听愉快!

节目制作人:

AlfieWearn

OmerFaruk Gulban

S4E10: NathanSpreng - Cognitive networks and how they vary with age and disease

If youare interested in working with Nathan, he is currently recruiting for apostdoc! Send your CV to lbc.spreng@gmail.com

Todayour guest is Nathan Spreng. Dr. Spreng is the James McGill Professor ofNeurology and Neurosurgery and Director of the Laboratory of Brain andCognition at the Montreal Neurological Institute and Hospital at McGillUniversity.

As anundergraduate, Dr. Spreng was initially interested in pursuing a major inpoetry until he took a psychology class that sparked his interest in the brain.He received Ph.D. in 2008 from the University of Toronto in Brian Levine's lab,and post docs with Cheryl Grady at the University of Toronto and Dan Schacterat Harvard. After about 5 years as an assistant professor at CornellUniversity, he moved to McGill University.

Throughouthis career Dr. Spreng has been using fMRI to reveal subtle yet repeatablelarge-scale brain networks as they relate attention, memory, cognitive control,and social cognition. He has also helped to elucidate the central role that thedefault network plays in self-generated thought, and in how it dynamicallyinteracts with multiple systems in the brain.

In thisepisode Peter and Nathan have a far reaching conversation about his work andwhat it implies, covering his study of age dependence of resting statehippocampal-linked network ensembles, how to move from mapping networks tomodeling and understanding mechanisms, the many possible clinical implicationsof his work, current understanding of Alzheimer's disease, our mutualappreciation for multi-echo EPI, his data release paper of a large multi-echoEPI and structural MRI data set, and much more.

Enjoylistening!

Episodeproducers:

AlfieWearn

OmerFaruk Gulban

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